Regenerative Therapy | Traumatic Brain Injury Protocol (Medical Ghostwriter Project)

Isabella Boston
May 5
36 min read

Updated: 1 day ago

Researched and Co-Written by Isabella Boston, Ghostwriter

The views expressed in this editorial are those of the author(s) and professional contributors of the 'Peter's Clinic'.

The Immersive Chemical Activation, Disruption & Entrainment (ADE) Protocol

Abstract

Objective

The Immersive, Electrical Cellular Activation, Disruption and Entrainment Protocol (ADE) is focused on the Central Nervous System (CNS). It uses such modalities as oxygen contrast therapy, sound and light frequencies, body to brain and brain to body educational functional health, and assistance in establishing new thought processes. In addition to focused medical and pharmacological examination, it centers around the fundamental components of life, such as breathing, movement, atmosphere, nutrition, sleep, and purpose.

Keywords

Immersive; Disruption; Entrainment; Adaptation; Regenerative; Medical Review.

Background

The Regenerative Therapy (RT) protocol directly targets brain and nerve function to activate the energy levels of the affected parts of the Central Nervous System (CNS). Using non-invasive and cutting-edge science we believe we can slow the progression, reverse, or outgain the loss of degenerative disease and limbic system impairment of the brain.

Individual Therapies/Modalities utilized within ADE Program:

Hyperbaric Chamber Tank (HBOT)
Whole body vibration therapy
Photobiomodulation
Neuro-bio stimulation
Interval/intermittent hypoxic training (IHT)
Hot/Cold Therapy
Pulsed Electromagnetic field therapy
7 Essential Elements

Also, when it comes to doing our ADE program in our acute treatment clinic, we use Sildenafil. “Sildenafil has been shown to significantly improve cognition and memory in preclinical models, presented as the best drug candidate,” Feixiong Cheng, PhD, the lead study author in the Cleveland Clinic’s Genomic Medicine Institute, said in a statement.

Materials and Methods Implemented:

The intake process starts with a consultation by our care team to review the patient’s health and medical history, pharmacological assessment, and possible replanning. The patient performs a CNS cognitive assessment to determine baseline.
Patients will also participate in a quantitative electroencephalography (QEEG). This “brain mapping” can measure brain waves in the brain, as well as the types that are flowing. The data can show brain function abnormalities and give additional insight into the patient’s cognitive and neurological performances.
Once data is collected and reviewed, the care team (consulting neurologist, medical provider, client advocate, coach, and physical therapist) creates a personalized game plan for the patient using protocols and therapies to help stabilize and improve performance.

Examples of these neurocognitive and behavioral assessments include:

Measuring the patient’s functional movement, balance, posture, body positioning and range of motion.
Using timed and patterned lights to analyze reaction times.
Perform the Pacific Clinic’s Oxygen Utilization Test.
Complete a computerized 3D body scan to track health metrics over time.

Summary

The ADE program is based on the principles of the brain’s capability to regenerate at the cellular level in addition to accessing better usage of the patient’s cognitive reserve. We focus on our ability as an organism to form and reorganize synaptic connections, as well as improve our usage of the functionality we have, through assistance by professional avocation, mentoring, and a team atmosphere.

The program teaches patients how to take control of their thought processes to force and maximize neuron-plasticity. It empowers entrainment and encourages rewiring of the limbic system, in addition to enabling possible improvement in the chemical makeup and change in the structure and functionality of the brain.

The consolidated concept of the ADE is to move patients towards physical and psychological healing. ADE is enabled by the supportive modalities which allows the patient to gain control of their health and restore losses or outgain the decline they are currently experiencing. This creates either an upward trend in their health or a reduced decline that they are predicted to endure.

The treatment seems to effectively work to regulate the maladapted stress responses involved with many chronic illnesses, cognitive impairment, and physiological traits patients have deemed insufficient deficiencies in maintaining a desired quality of life.

The brain is the control center for optimal health and drives the functions of all systems of the body. The limbic system is a complex set of structures in the midbrain and is associated with emotion, learning, memory, and the body’s stress response. Chronic or degenerative disease of various forms of trauma, such as a viral or bacterial infection, extreme emotional or psychological stress, toxic exposure to chemicals or mold, physical injury, in addition to many other forms of trauma can cause threat circuits in the brain’s limbic system to fire more rapidly.

This is the brain’s innate response to stress and trauma; however, in most cases the brain’s limbic system can get stuck in a chronic fight, flight, or freeze response and become impaired. This seems to be an exacerbating contributor to most degenerative diseases as well as concussions and other external neurological causations.

The maladapted stress response is called Limbic System Impairment. The brain and body remain on high alert, even if the initial threat or trauma is no longer present. It is caused by a single trauma, or in most cases from a combination of stressors and traumas contributing to the effects of the degenerative process, as well as reducing the ability for successfully treating the core cause of the decline. For many it is at the very root of their ongoing suffering and their loss of hope to beat their disease.

Modalities, Treatments, and Processes

Electrochemical Stimulation

Superset Stack Recovery Protocol (SSR) (Hyperbaric Oxygen Therapy [HBOT]. Whole Body Vibration, Oxygen Contrast Therapy, and lung and circulatory stretch), are used to create intermittent hypoxia, increased blood flow, greater perfusion of oxygen into the tissue, electrochemical stimulation, as well as prepare the brain for further stimulation with sound and light frequencies.

We stack our modalities (SSR) based on the research, believing that the coupling provides exponential results as each modality allows for better results with the corresponding processes.

Transcranial Photobiomodulation Therapy (PBM-T or tPBM) is a nonthermal automation used to activate cellular activity using near-infrared light (NIR). Light is set at an amplitude and directed at penetrating through the cranium to encourage ATP activation and production. Pulsating frequenting is set directionally with the amplitude set specifically from the patient’s prescribed QEEG results. Most patients range from a frequency of 10 Hz to 40 Hz, with 40 Hz being the most used to encourage neural stimulation; even increasing the flexibility of the endothelial cell’s usage is directed by our partner neurologist who additionally is a QEED-D.

A pilot study, conducted by the National Institutes of Health (NIH), used NIR 1068 nm transcranial photobiomodulation therapy and concluded that “it may be a promising new approach to improve memory in healthy middle-aged individuals .” Patients were successful in utilizing a tPBM helmet to self-deliver the treatment and no adverse side effects were reported.

The results showed a remarkable improvement in memory performance, motor function, and processing speed in healthy persons aged 45 years and older in comparison to a placebo group.

Durham University conducted an Alzheimer’s at-home pilot study which also resulted with positive and profound effects for both women and men suffering from mild to moderate dementia. The participants had improved energy, less anxiety, elevated mood, and an overall physical and mental well-being in their day-to-day activities. These results were also observed and noted by their caretakers.

In their recent pilot study, results concluded a significant improvement in motor performance function (finger tapping), memory performance (processing mathematical data, a type of working memory), and delayed brain and memory processing speed. Study was performed on healthy individuals aged 45 and above who received six minutes of therapy twice a day using a wavelength of 1068 nanometers over a course of four weeks.

Scientists believe the therapy could also provide potential benefits for individuals suffering from Parkinson’s, motor neuron disease, and traumatic brain injuries.

Disruption, Entrainment and Retraining

Neuro-Stimulation

Neurobiology Stimulation using sound frequencies has proven to have positive effects with Alzheimer’s and Parkinson’s patients., Through binaural stimulation therapy, a binaural beat is created. This takes place when one ear hears one tone, and the other hears a tone within 25 Hz of the first frequency which causes the brain to effectuate a third frequency.

Exploiting this natural mechanism of the brain, and specifically the reaction from the vagal nervous system and the polyvagal system; binaural beats have been shown to influence a wide degree of physical and mental ailments affected by the polyvagal system.

We also do this using spatial sound, or 8D, surround sound. An important element is to refrain from using loud as well as too many frequencies.

Spatial sound works by using volume and shifts in the surround-sound location the audio is transmitting from. This is done using surround sound speakers to create the audio experience. Additionally, the patient has a home unit that allows similar responses using a surround sound headset. This process stimulates the inner ear, the proprioception network, and deepens immersion in acoustic therapy using specific frequencies that research has proven to have positive effects on 432 that research has proven to have positive effects on HRV, as well as specific degenerative diseases. We mix this with a biofeedback breathing program and visual awareness exercises producing effective neurofeedback.

Additionally, the song is remixed at a frequency of 428 which has been shown to be calming. Other frequencies are used sparingly, however individual research found to be beneficial with the specific patient’s diagnostic profile. Again, the most used frequency is 40 Hz. This is coupled with the biofeedback protocol while visually focusing on ten-second meditative visual breathing, adherent and practicing a balance program with proprioception spatial awareness drills.

We have independently measured increases in heart rate variability (a new standard for neural health) when applying dimensional audio techniques to binaural stimulation in addition to regulating the blood pressure through producing a negative loop in the heart lowering blood pressure and stabilizing heart function.

Further medical investigations are necessary to discover the full potential of this technology, but what seems undeniable is that immersion has a drastic effect on our therapeutic processes, the Central Nervous System, and throughout the body.

Pain and Stress Management

Hot and Cold Therapy

Challenging the body using a sauna and a cold therapy pool has become the catalyst to our whole protocol. Autophagy, mitochondrial biogenesis, and mitophagy are essential to healing and are maximized while experiencing cold therapy. Cold activated brown adipose tissue (BAT) mitochondrial biogenesis is recognized as critical for thermogenic adaptation and challenges which improves the brain’s ability to clean itself and allows for better prospective, disposition, positive effects on tinnitus, headaches, restoring sleep as well as setting the stage for better thought processes. This coupled with heat sessions is very effective. Heat therapy has been independently shown to reduce whole body insulin resistance, improve vascular function, activate interorgan crosstalk via endocytic vesicles, and activate Heat Shock Protein (HSP) to improve mitochondrial function and proteostasis in a variety of tissues. The combining of the two therapies have not been well researched as far as needing to be in sequence as far as causing additional benefits yet imperially, we have found the combination increases relaxation as well as improves rest and reduces levels of stress.

Sauna use is an ancient practice that has been used for the purpose of therapy, cleansing, and healing by many cultures for thousands of years. The treatment is also known as “sauna bathing”.

According to Dr. Rhonda Patrick, a well -recognized biochemist and scientist; sauna therapy and heat stress has been known to increase Brain-Derived Neurotrophic Factor (BDNF) and norepinephrine (a protein that activates new brain-cell growth), improve endurance in athletes, increase longevity, improve insulin sensitivity, by boosting glucose receptors within the muscle cells, and prevent muscle atrophy.

Dr. Patrick goes on to say, “‘Sauna bathing’ is characterized by short-term passive exposure to extreme heat. This elicits mild hyperthermia – an increase in the body’s core temperature – that induces thermoregulatory response involving neuroendocrine, cardiovascular, and cytoprotective mechanisms that work together to restore homeostasis and condition the body for future heat stressors.”

Her findings are supported by the Kuopio Ischemic Heart Disease Risk Factor (KIHD) study, published by JAMA International Medicine, which showed evidence of decreased disease and death linked to sauna use. The study involved more than 2,300 middle-aged men from Finland and results concluded that those who used the sauna two to three times a week were less likely to die from cardiovascular related diseases by 27% compared to men who did not. Furthermore, participants who continued to frequently use the sauna were 40% unlikely to die a premature death.

Evidence further concluded that continued use of the sauna, four to seven times per week, also decreased the chance of developing Alzheimer’s and dementia by 66%. Participants in the KIDH study also were less likely to develop psychotic and mental disorders, regardless of their socioeconomic status, dietary habits, and fitness levels.

Cold therapy is also an ancient practice for good health that dates back for many centuries. Today it is used to mainly promote muscle recovery and reduce soreness. Regular exposure to cold may improve glucose and lipid metabolism, enhance immune function, decrease inflammation, and improve cognitive performance. These benefits could be linked to hormesis, an approving biological response to mild stressors.

According to Dr. Patrick, exposure to cold therapy causes cold shock response, a range of acute physiological responses. The intention of cold shock response is to decrease loss of heat and increase heat production,. Repeated exposure causes the body to become accustomed to the cold, known as habituation, reducing the cold shock response.

An increasing amount of evidence suggests cold therapy exposure affects multiple organ systems, evoking positive effects on conditions with metabolic, immune, cardiovascular, and neurocognitive health.

Intermittent Hypoxia and Apnea Training

Using the approaches to internal regulation through breath work, intermittent hypoxia therapy and apnea training is accepted by medical literature to have the effect of internal regulation by controlling concentrations of several key factors with a result of increase oxygen usage.

One key research we base our concept on came out of the University of Tel Aviv (UT) showing the effects of intermittent hypoxia by the method of using Hyperbaric Oxygen Therapy (HBOT). We use HBOT as well, but only for a limited time with most patients during the first three weeks. However, we found the Oxygen Contrast Therapy (OCT) to be far more effective for degenerative diseases.

We also assume from the research from UT that our patients would receive the same benefits at the cellular level as was found using the HBOT. In fact, if it is true what the UT research found, that the significant benefit from the HBOT was because of Intermittent Hypoxia, then we believe our program would be more effective as there is much more proactive Intermittent Hypoxic processes.

We also extract what we learn in our acute in-clinic therapy, as mentioned above, and have applied it to a home-breathing, frequency-movement program that is significant in its effectiveness when continued through the day outside the clinic.

We garner very similar Intermittent Hypoxia results while doing this program out of the clinic. Vasodilation, blood flow, O2, CO2 exchange in the body affects every system in the body and the ability for the body to gain functionality which affects its ability to heal.

These methodologies also affect the nervous system by encouraging a long-lasting parasympathetic state and for some of our patients this is the only way to get them into that state. We also see great improvements in the patient’s Heart Rate Variability (HRV) daily averages.

Nutrition Process of the Protocol

Process starts with a one to four- day fast with most patients doing a 40-hour water fast ending on Tuesday morning. Patients the care team deems capable, and believe there is added value, can continue the fast for up to four days.

If they are not capable of the fast, then they are to start a three-day live diet consisting of high microbiome supportive intake of fermented foods and a diversity of fruits and vegetables. This is what we have our patients continue with as a refereeing if they have attempted the fast.

After the fast, patients are asked to begin, a minimum 12- hour preferably, 16-hour intermittent fast daily. And on Sunday to have an early breakfast and lunch of their choice before returning to the weekly 40-hour fast.

As stated above, re-feeding starts with a microbiome diverse diet with no processed foods or sugars. Both keto and plant-based keto diets are recommended. They are recommended to only use non-pasteurized whole milk that is A2 protein, coconut milk, or other non-sweetened milk replacements.

It is also recommended to ingest only unprocessed or refined honey, organic 100% maple syrup, or Monk Fruit to sweeten any intake, preferably after week three. They are further asked to keep sweetened intake down to no more than one meal a day after the 4th week.

7 Essentials: Out of Clinic (the other 20 hours)

Thought

Thought, or maybe better stated, the process of acquiring the processes to think on purpose, is a significant, if not crucial process, to neuroplasticity. We believe that the rest of the protocol including in-clinic acute modalities are limited without this concrete process being the center focus of all in- clinic treatments. This is also essential that the other 20 hours of the day are consciously being evaluated as to the improvement in controlling thought to be true and on purpose.

Research from Huberman Lab at Stanford emphasizes that we cannot lie to our brain. The brain knows we are not being truthful about thinking positive unless we truly develop the process to interpret life as positive. The growing effect of doing so gleams previously unreachable results within all the program when this is learned. We have also grown to understand this is set on a proper course for most patients by the coach/mentor. We have learned to lean on the concept of thinking for them. By convincing them they can allow us this leadership and if enough trust is established it’s adaptable to the results of them controlling these processes and controlling their ability to think on purpose.

This process is approached in incremental steps to allow the person the ability to perceive what is transpiring during the changes. Through this exercise it’s important to train them to understand we cannot just say we are going to think positive; we must purposefully give ourselves positive events and items to think positive about. By filtering thoughts, they can control their physical and psychological health.

Atmosphere

We live in a 75-degree world. Our houses are 75 degrees, our offices are 75 degrees; restaurants, malls, schools are all 75 degrees. This prevents our systems from ever being challenged, and challenge is what makes ourselves better. If we want a muscle to grow, we over work it. We challenge it and it responds. The same is true with our systems: hormone, microbiome, immune, and pretty much every system of our body. By getting outside, our body must adapt and regulate itself. We must adjust, even transform to the atmosphere. Additionally, we get much needed adaptations to regular challenges.

We like to get in the water, get in the mud, and get in the hot or cold. Take our shoes off and lower our levels of radiation we receive from living within all our electric and magnetic fields put off by our devices and lights and modern surroundings. Many refer to this as (EMFs) and getting out in nature can bring us to the levels we need which happens to be the lowest possible.

By getting out in the atmosphere we can soak in the giver of life, the sun. It is what provides the beginnings of everything healthy. For instance, vitamin D. It is thought to be a vitamin because it must be ingested, but it is very much like a hormone. We can be in the sun and activate it within our system. We should also say atmosphere is one of the seven essential elements as it pertains to thought. We need to get a personal space that is of peace. This is to say we need to think on purpose. Do not put ourselves in an atmosphere that is full of negativity or stress. So, in this way the atmosphere is kind of a double meaning. Purposefully make our days surrounded with the most peaceful and rewarding settings we can. So indoors or out, seek out positive input but do not forget how easy that is if we use nature to spur our challenges in other ways to initiate our ability to get out of sympathetic zones into a parasympathetic relaxation state.

Breathing

We jokingly say, “come to find out breathing is good for you.” Here is the fact: Most of us do not know how to breathe, and the reality is that none of us breathe optimally all the time. We teach programs that help us improve our Heart Rate Variability (HRV). We can even use our breathing to create a more effective negative feedback loop for our blood pressure. This is done by controlling our breathing which allows the baroreflex or sometimes called the baroreceptor reflex which provides a rapid negative feedback loop in which an elevated blood pressure causes the heart rate to decrease IE negative feedback loop.

Additionally in our breathing programs we learn how to raise our excitement levels or conversely use breathing to calm our system. We also use breathing teamed with sound frequencies to calm the storm in our brain and allow breathing exercises to challenge our systems, excite, or activate our neurons and nervous systems. We use it to teach our hemoglobin to carry more oxygen and better facilitate the use of the oxygen and maybe more importantly teach our bodies to better have better profusion of the oxygen into our tissue. We believe this is one of the best ways to improve degenerative disease.

In all our programs we never claim we can cure or get rid of degenerative disease, but our thoughts are: What if we can outgain the loss? What if we can improve more than we lose? What if by providing the body and brain the right resources, we can go where we have never gone before?

To do this we have to provide the greatest of natural resources, and we attempt to do this from the greatest of resources: Light, nature, proper nutritional resources, and, yes, oxygen is probably the most valuable of nutritional resources.

Movement

We strongly believe in the concept of body training brain. Our patients work with our coaches, athletic trainers, and physical therapists to design patient- specific sports and movement activities to further advance their recovery. One key to our movement concept is differentiated movements that are performed in a flow concept, which is to say continuation of new movement yet couched in a low risk of injury or setback, as well as exacerbated frustration from limited success in the function.

Research has shown that doing a one-minute major muscle movement can raise the metabolism as much as 43%. In doing this the patient does not retain that metabolism bump, yet they do start to trend better throughout the 24 hours.

Additionally, by getting the metabolism elevated the patient has increased blood flow, and when done with a breathing routine they start to calm their mind as well as think more clearly. We believe our clinic program has significant supportive benefits to our in-clinic oxygen contrast therapy during the acute phase of treatment and in time can continue the progress out of the clinic after the treatment.

We prefer movement instead of exercise. The most important time for our patients is the 20 hours a day outside of our clinic. And yes, exercise is great but truthfully not as important as the totality of movement throughout the day. We work to keep moving and we encourage people to do what we call quick sets to amp up their circulation and even metabolism by doing as little as one-minute major muscle movements four to seven times a day.

Research has shown that in that one minute they can raise their metabolism as much as 43% from their sitting metabolism. Additionally, we have them walk or swim. We prefer smooth movements because one, we don't want setbacks that come from injuries from unanticipated movement and two, because walking and swimming can affect their outlook and start to tap into their parasympathetic system as they learn to couple movement with proper thought. However, movement has a double meaning as we are also talking about movement within the body. We teach people to stretch to move full range of motion and to sit and stand properly to ensure that the body can flow and move within itself.

If a bear came up behind you, you speed off your body’s reaction, and let’s just say it would be memorable. Within ten of a second your system springs into action. Well, that same flow of chemicals can take place all the time, but when we sit or stand wrong it is almost like putting kinks in the hose. We need to ensure all the inclusive work we are doing gets full usage.

From breathing, to eating, to neurostimulation, by learning to put our bodies in the right positions we can maximize the movement and accessibility to all our systems to do what they do best, help us heal.

Sleep

Maybe the most important part of healing is sleep. We may not know this but everything, even the thinking drills and other efforts reap their gain while we sleep. We can’t heal if we don’t sleep.

Some people this thought can even cause anxiety because they think wow, I don’t sleep how will this program work? The sleeping brain replays the day's experiences and stabilizes them by moving them from the hippocampus, where they are first formed, to regions across the brain. We believe it is probably true with positive emotions as well as reaping the benefits of physical and chemical positive changes within our program.

Again, we don’t stress people about sleep, we just help them build routines to help facilitate sleep and just as important quality of sleep.

Nutrition

This thought to be the most important, and for sure it is very important, but, again, we attempt to not make alterations that make this a full-time job. We keep it as simple as possible. We start with a strict elimination diet and move to a straightforward principle that we believe are key.

Stay away from all processed foods and man-made ingredients.
Remove quick hitting sugars, and if needed, use the most natural sugars that have more value such as local honey which can help the microbiome. Keep sugars to a very minimum.
Limit or greatly restrict grains especially those that are processed by man.
Make diet as diverse as possible with emphasis on food that can maximize one’s microbiome IE fermented foods, diverse vegetables, low sugar fruits, and natural fats such as organic butter, gee, olive oil, coconut oil, and even whole raw milk.

Purpose

Much research has been coming to light that as humankind to be fully healthy we need to have purpose; this isn’t to say we must have a plan to change the world, but center on a plan that changes the world we live in. Help the people that are daily in our path. Dr. Huberman from Stanford University says the biggest gains from gratefulness is about experiencing people being grateful for what we have done for them. It’s possibly literally in our DNA to live our lives and feel we are impacting the people in our life.

Glossary and Explanation of ADE Protocol Terms

10 Hz.: A 10 Hz rhythm is present in the occipital cortex when the eyes are closed (alpha waves), in the precentral cortex at rest (mu rhythm), in the superior and middle temporal lobe (tau rhythm), in the inferior olive (projection to cerebellar cortex), and in physiological tremor (underlying all voluntary movement). These are all considered resting rhythms in the waking brain which are “replaced” by higher frequency activity with sensorimotor stimulation. That is, the 10 Hz frequency fulcrum is replaced on the one hand by lower frequencies during sleep, or on the other hand by higher frequencies during volition and cognition. The 10 Hz frequency fulcrum is proposed as the natural frequency of the brain during quiet waking but is replaced by higher frequencies capable of permitting more complex functions, or by lower frequencies during sleep and inactivity. At the center of the transition shifts to and from the resting rhythm is the reticular activating system, a phylogenetically preserved area of the brain essential for preconscious awareness.
40 Hz Background: Exercise promotes brain health and improves cognitive functioning in the elderly, while 40-Hz light flickering through the visual cortex reduces amyloid beta (Aβ) by stabilizing gamma oscillation. We examined whether exercise was associated with hippocampus-mediated improvement in cognitive functioning in the 3xTg-Alzheimer’s disease (3xTg-AD) murine model following exposure to 40-Hz light flickering and exercise.
Methods: We subjected 12-month-old 3xTg-AD mice to exercise and 40-Hz light flickering for 3 months to investigate spatial learning, memory, long-term memory, Aβ levels, tau levels, mitochondrial functioning including Ca2+ retention and H2O2 emission, apoptosis, and neurogenesis in the hippocampus.
Results: Treatments had a positive effect; however, the combination of exercise and 40-Hz light flickering exposure was most effective in reducing Aβ and tau levels. Reducing Aβ and tau levels by combination of exercise and 40-Hz light flickering improves Ca2+ homeostasis and reactive oxygen species such as H2O2 in mitochondria and apoptosis including bax, bcl-2, cytochrome c, and cleaved caspase-3 and cell death, cell differentiation, and neurogenesis in the 3xTg-AD model of the hippocampus, resulting in improving cognitive impairment such as spatial learning, memory, and long-term memory.
Conclusion: Our results show that exercising in a 40-Hz light flickering environment may improve cognitive functioning by reducing AB and tau levels, thereby enhancing mitochondrial function and neuroplasticity.
432 Hz: Music tuned to 432 Hz is softer and brighter and is said to provide greater clarity. It is also easier on the ears. Meditation music tuned to 432 Hz is relaxing for the body and mind and more harmonic and pleasant than the modern-day frequency of 440 Hz. 432 Hz tuned music was associated with a slight decrease of mean (systolic and diastolic) blood pressure values (although not significant), a marked decrease in the mean of heart rate (-4.79 bpm, p = 0.05) and a slight decrease of the mean respiratory rate values (1 r.a., p = 0.06), compared to 440 Hz. The subjects were more focused about listening to music and more generally satisfied after the sessions in which they listened to 432 Hz tuned music. Conclusions: The data suggests that 432 Hz tuned music can decrease heart rate more than 440 Hz tuned music. The study results suggest repeating the experiment with a larger sample pool and introducing randomized controlled trials covering more clinical parameter.
8D audio: An effect applied to a stereo track where songs have been edited with spatial reverb and mixing to make it seem like the audio moving in a circle around your head.
A standard electroencephalogram (EEG): Records electrical activity or brain waves that are representative of underlying cortical brain activity. A quantitative EEG (qEEG) applies sophisticated mathematical and statistical analysis to these brainwaves and compares them to age and gender control.
Alzheimer’s: A progressive disease that destroys memory and other important mental functions. Brain cell connections and the cells themselves degenerate and die, eventually destroying memory and other important mental functions.
Apnea Training: Breath training will improve the way in which oxygen is released from hemoglobin as it is transported around the body and decreases the chances of excess carbon dioxide build up within the tissues, creating an acidic environment where oxygen will not be readily absorbed into the blood.
Autophagy: Consumption of the body’s own tissue as a metabolic process occurring in starvation and certain diseases. "The process of starvation-induced autophagy was recently the focus of extensive research."
Baroreceptors: Spray-type nerve endings in the walls of blood vessels and the heart that are stimulated by the absolute level of, and changes in, arterial pressure. They are extremely abundant in the wall of the bifurcation of the internal carotid arteries (carotid sinus) and in the wall of the aortic arch. The baroreflex or baroreceptor reflex is one of the body's homeostatic mechanisms that helps to maintain blood pressure at nearly constant levels. The baroreflex provides a rapid negative feedback loop in which an elevated blood pressure causes the heart rate to decrease.
BDNF: Brain-Derived Neurotrophic Factor is a secreted protein that regulates many aspects of neuronal development and function in the nervous system.
Binaural Stimulation: Binaural beats are an auditory illusion caused by listening to two tones of slightly different frequency, one in each ear. The difference in frequencies creates the illusion of a third sound -- a rhythmic beat. Neurons throughout the brain begin to send electrical messages at the same rate as the imaginary beat.
Binaural beats benefits: We use Binaural as a means of disruption, entrainment and retraining of the cognitive function. It is best done immediately, and we believe will have no effect if not done within a few hours of activation of cells. Binaural sound wave therapy has shown improvements such as binaural sound increases creativity and cognitive enhancement. Reduces anxiety and improves mood. Helps patients enter a meditative state. It also Improves sleeping habits. Helps to improve focus, attention, and memory retention.
Biogenesis: The synthesis of substances by living organisms.
Blood Pressure: The results are given in two numbers. The first number, called systolic blood pressure, is the pressure caused by your heart contracting and pushing out blood. The second number, called diastolic blood pressure, is the pressure when your heart relaxes and fills with blood.
Brown Adipose Tissue (BAT): Brown fat, also called brown adipose tissue, is a special type of body fat that is turned on (activated) when you get cold. Brown fat produces heat to help maintain your body temperature in cold conditions. Brown fat contains many more mitochondria than does white fat. BAT has been shown to be an important support for brain function.
Central Nervous System (CNS): The nervous system is organized into two main parts, the central nervous system, and the peripheral nervous system (PNS). The CNS is the processing center of the body and consists of the brain and the spinal cord.
Chronic illnesses: A human health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time. The term chronic is often applied when the course of the disease lasts for more than three months.
Cognitive impairment: When a person has trouble remembering, learning new things, concentrating, or making decisions that affect their everyday life. Cognitive impairment ranges from mild to severe.
Cognitive Reserve: Refers to individual differences in how tasks are performed that may allow some people to be more resilient than others. The concept of cognitive reserve holds out the promise of interventions that could slow cognitive aging or reduce the risk of dementia. We help the brain regenerate or whatever the neuroplasticity, but we are also taking advantage of their cognitive reserve.
Degenerative disease: The result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time. In neurodegenerative diseases, cells of the central nervous system stop working or die via neurodegeneration.
Diagnostic Profile: This article introduces the Diagnostic Profiles (DP) standard setting method for setting a performance standard on a test developed from a cognitive diagnostic model (CDM), the outcome of which is a profile of mastered and not-mastered skills or attributes rather than a single test score.
Disruption: a breakdown or interference with a normal process or structure, often leading to an abnormal or damaged state.
EEG: An EEG is a test that detects abnormalities in your brain waves, or in the electrical activity of your brain. During the procedure, electrodes consisting of small metal discs with thin wires are pasted onto your scalp. The electrodes detect tiny electrical charges that result from the activity of your brain cells.
Electrical Chemical Activation:
Electromagnetic Field (EMF): An electromagnetic field is a classical field produced by accelerating electric charges. It is the field described by classical electrodynamics and is the classical counterpart to the quantized electromagnetic field tensor in quantum electrodynamics.
Electrochemical Stimulation: We work to stimulate our bodies at a cellular level by either activating them electrically trough frequencies excursion hot and cold therapy, we additionally do this by providing the oxygen and nutrients needed to cause chemical change. The elements in our bodies, like sodium, potassium, calcium, and magnesium, have a specific electrical charge. Almost all our cells can use these charged elements, called ions, to generate electricity. The contents of the cell are protected from the outside environment by a cell membrane.
Entrainment: An important characteristic of interactions between brain rhythms and refers to the coupling of two independent oscillatory systems in such a way that their periods of oscillation become related by virtue of phase alignment.
Exacerbating: Make a problem, bad situation, or negative feeling worse. "The exorbitant cost of land in urban areas only exacerbated the problem."
Fasting: In our protocol we suggest a non-calorie fast from Sunday afternoon until Tuesday AM. For some patients this is not recommended especially for many diabetes patients and for others we take it as long as 96 hours. We have found that there are minimum gains past that time. Within the fast it allows the body to lower inflammation as well as calm the mind and even improves Tinnitus for many of the patients.
Fight or flight: The sympathetic nervous system functions like a gas pedal in a car. It triggers the fight-or-flight response, the instinctive physiological response to a threatening situation, which readies one either to resist forcibly or to run away.
Flow Concept: Our term for creating good posture and positioning of the body to maximize blood flow in addition to other positive chemical releases within the body. We also use it to describe how the physical body moves throughout the day and night to minimize opportunity for structural insecurity
Heart Rate Veritably (HRV): Heart rate variability biofeedback (HRV-BFB) training, a method whereby one controls an unusually low breathing rate to reach cardiac coherence, has been shown to reduce anxiety and improve cardiac autonomic markers in diseased people, but much less is known about HRV-BFB benefits in healthy people.
Heat Shock Protein (HSP): Heat shock proteins are a large family of molecular chaperones that are well-known for their roles in protein maturation, re-folding, and degradation. While some HSP’S are constitutively expressed in certain regions, others are rapidly upregulated in the presence of stressful stimuli. Reparation of misfolded and damaged proteins. HSP Increased immune response. Reduce free radicals. They make faster muscle recovery and repair. They protect the heart. They cause higher insulin production.
Heat Therapy: Heat therapy can reduce mental stress, as indicated by cortisol levels in the blood, and reduce oxidative stress on a chemical level. It’s also known to assist in the release of EPO Erythropoietin (EPO) is a hormone produced by the kidney that promotes the formation of red blood cells by the bone marrow. The kidney cells that make erythropoietin are sensitive to low oxygen levels in the blood that travels through the kidney. We also attempt to release EPO using Apnea breathing techniques during oxygen contrast therapy Additionally Heat therapy causes the release of BDNF The BDNF gene provides instructions for making a protein found in the brain and spinal cord called brain-derived neurotrophic factor. This protein promotes the survival of nerve cells (neurons) by playing a role in the growth, maturation (differentiation), and maintenance of these cells. We believe that combining with the stacked therapy of Cold water that the combination causes greater release of ATP and Biogenesis of mitochondria causing the Heat Therapy results to be more substantial.
Hertz: The SI unit of frequency, equal to one cycle per second.
Hyperbaric Oxygen Therapy
Hyperbaric: Hyperbaric medicine is medical treatment in which an ambient pressure greater than sea level atmospheric pressure is a necessary component.
Hypercapnia: Most research says Hypercapnia is excessive carbon dioxide in the bloodstream, typically caused by inadequate respiration. The key word is respiration; we found that with most of our obese or degenerative disease patients that they experience Hypercapnia even with excessive oxygen, especially externally provided oxygen. (Similar to them over exerting.) We found that our therapy helped the body start to have proper perfusion of oxygen into the cells; not just increase in ventilation.
Hypoxia: An absence of enough oxygen in the tissues to sustain bodily functions. We consider hypoxia to be below 92%.
Innate: Existing in, belonging to, or determined by factors present in an individual from birth: native, inborn innate behavior. 2: belonging to the essential nature of something: inherent. 3: originating in or derived from the mind or the constitution of the intellect rather than from experience.
Insulin Resistance: The hormone insulin helps control the amount of sugar (glucose) in the blood. With insulin resistance, the body's cells don't respond normally to insulin. Glucose can't enter the cells as easily, so it builds up in the blood. This can eventually lead to type 2 diabetes.
Insulin: A hormone produced in the pancreas by the islets of Langerhans, which regulates the amount of glucose in the blood. The lack of insulin causes a form of diabetes.
Intermittent Fast: Intermittent fasting, also known as intermittent energy restriction, is any of various meal timing schedules that cycle between voluntary fasting and non-fasting over a given period. Methods of intermittent fasting include alternate-day fasting, periodic fasting, and daily time-restricted feeding. For our patients we recommend a minimum of 12 hours with many going as much as 16 hours every day except Saturday and Sunday until 5 pm.
Intermittent Hypoxia: Intermittent hypoxia (also known as episodic hypoxia) is an intervention in which a person or animal undergoes alternating periods of normoxia and hypoxia. Normoxia is defined as exposure to oxygen levels normally found in earth's atmosphere (~21% O2) and hypoxia as any oxygen levels lower than those of normoxia
Limbic system impairment: Limbic ADD is a serious disorder involving a very specific set of complex structures within the brain, and manifesting symptoms like clinical depression. Without proper treatment, those experiencing the effects of Limbic ADD are at risk of having their lives becoming very dysfunctional and unhappy.
Limbic system: The part of the brain involved in our behavioral and emotional responses, especially when it comes to behaviors we need for survival: feeding, reproduction and caring for our young, and fight or flight responses.
LiveO2: The currently chosen equipment we use for our Acute Oxygen Contrast Therapy creating Intermittent hypoxia and assisting us in teaching proper breathing techniques as well as enabling us to take limited mobility patients into an aerobic state.
Medical Provider: In the state of Washington this can be referring to a medical doctor or Nurse Practitioner.
Metabolism: The chemical processes that occur within a living organism to maintain life.
Microbiome: The microorganisms in a particular environment (including the body or a part of the body). "We depend on a vast army of microbes to stay alive: a microbiome that protects us against germs, breaks down food to release energy, and produces vitamins."
Mitochondria: An organelle found in large numbers in most cells, in which the biochemical processes of respiration and energy production occur. It has a double membrane; the inner layer being folded inward to form layers (cristae). Due to their central role in cell life and death, mitochondria are also involved in the pathogenesis and progression of numerous human diseases, including, among others, cancer, neurodegenerative and cardiovascular disorders, diabetes, traumatic brain injury, and inflammation.
Mitochondrial Biogenesis: Mitochondrial biogenesis is the process by which cells increase mitochondrial numbers. In the 60’s it was found that physical endurance training induced higher mitochondrial content levels, leading to greater glucose uptake by muscles. It is now known other processes cause Mitochondrial Biogenesis such as Cold therapy, intermittent fasting.
Monk Fruit: It is native to southern China and northern Thailand. The plant is cultivated for its fruit extract, called mogrosides, which creates a sweetness sensation 250 times stronger than sucrose. We use it as a main source of sweetness for those needed during the first 3 weeks of our program.
Multiple System Atrophy (MSA): A rare neurodegenerative disorder that can cause a multitude of symptoms in any combination including impairments to balance, difficulty with movement, poor coordination, bladder dysfunction, sleep disturbances and poor blood pressure control. We believe this is what people see with environmental toxicity causing symptoms and diagnosed as Parkinson’s. This keeps us focused on blood pressure and reduction of toxicity.
Negative Loop in Heart: The baroreflex provides a negative feedback loop for controlling blood pressure, such that heart rate falls when blood pressure rises, and vice-versa when blood pressure falls, thus modulating blood pressure fluctuations.
Oxygen Contrast Therapy: Creating Intermittent hypoxia (also known as episodic hypoxia) is an intervention in which a person undergoes alternating periods of normoxia and hypoxia. Normoxia is defined as exposure to oxygen levels normally found in earth's atmosphere (~21% O2) and hypoxia as any oxygen levels lower than those of normoxia. We use around 15%. Our treatment goal is to take most the patient to under 92% oxygen saturation for a period of 1 to 3 minutes and return them to 96 % or greater and repeat the process 3 to 7 times ending with 3 minutes of what I refer to as upper homeostasis 97 to 100% before removing external oxygen>
Parasympathetic Nervous System: The parasympathetic nervous system predominates in quiet “rest and digest” conditions while the sympathetic nervous system drives the “fight or flight” response in stressful situations. The main purpose of the PNS is to conserve energy to be used later and to regulate bodily functions like digestion and urination.
Parkinsonism: Any condition that causes a combination of the movement abnormalities seen in Parkinson's disease — such as tremor, slow movement, impaired speech, or muscle stiffness — especially resulting from the loss of dopamine-containing nerve cells (neurons).
Parkinson’s Disease: A disorder of the central nervous system that affects movement, often including tremors. Nerve cell damage in the brain causes dopamine levels to drop, leading to the symptoms of Parkinson's.
Perfusion: Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue. Perfusion is measured as the rate at which blood is delivered to tissue, or volume of blood per unit time per unit tissue mass. As it pertains to our program, perfusion is the term used to how we believe the oxygen is being utilized within the tissue. In most cases we can see when a patient starts our program, they have very little usage. As we introduce our breathing techniques as well as Oxygen Contrast Therapy, they begin to use much more of the oxygen they are ventilating into their lungs. This is monitored during OCT using a peripheral oxygen saturation device on their middle figure of their dominant hand. It is evaluated using two breathing techniques one) our over ventilation technique followed by a measured maximization of holding the breath. And two) an over ventilation exercise followed by a slow breath out to see the gains in the time they can expel. Typically, we see over 100% or greater gains within 4 to 8 weeks.
Peripheral Nervous System (PNS): A network of nerves extending from the central nervous system (brain and spinal cord) to the rest of the body.
Polyvagal: Polyvagal theory is a collection of unproven evolutionary, neuroscientific, and psychological constructs pertaining to the role of the vagus nerve in emotion regulation, social connection, and fear response. We believe there is some truth to these claims and find it to seem to have direct correlation to our patients’ feelings and attitude. We focus on improving vagal nerve stimulation and improving HRV and get improved mood and energy levels. This may be from belief only but either way it is effective.
Post-Concussion Syndrome (PCS): Persistent post-concussive symptoms, also called post-concussion syndrome, occurs when concussion symptoms last beyond the expected recovery period after the initial injury. The usual recovery period is weeks to months. These symptoms may include headaches, dizziness, and problems with concentration and memory.
Proprioception: Perception or awareness of the position and movement of the body. Exercises to improve balance and Proprioception, also referred as kinesthesia, is the sense of self-movement and body position. It is sometimes described as the "sixth sense". Proprioception is mediated by proprioceptors, mechanosensory neurons located within muscles, tendons, and joints.
Proteostasis: Protein homeostasis or 'proteostasis' is the process that regulates proteins within the cell to maintain the health of both the cellular proteome and the organism itself. Proteostasis involves a highly complex interconnection of pathways that influence the fate of a protein from synthesis to degradation.
QEEG-D: A medical professional who has the certification to read QEEG’s allowing accurate usage of Transcranial PBM.
QEEG: A qEEG (Quantitative Electroencephalogram) is a diagnostic tool that measures electrical activity in the form of brain wave patterns. It is sometimes referred to as “brain mapping.” The EEG and the derived qEEG information can be interpreted and used by experts as a clinical tool to evaluate brain function, and to track the changes in brain function due to various interventions such as neurofeedback or medication.
Senescent Cells: Senescence is Cellular senescence is a phenomenon characterized by the cessation of cell division. Normal human fetal fibroblasts in culture reach a maximum of approximately 50 cell population doublings before becoming senescent, the condition or process of deterioration with age. Loss of a cell's power of division and growth.
Spatial Awareness: An organized awareness of the objects in the space around us, and an awareness of our body's position in that space. Knowing where your body is in space in relation to objects or other people. To have good spatial awareness you also need to understand and respond to a change in position from these objects. This is a complex skill that children develop from an early age.
Stacked Protocol: Use of a combination of modalities to maximize effectiveness of the individual parts of the protocol.
Sundowners syndrome: Also called sundowning or late-day confusion, is a group of symptoms that occur in someone with memory loss that can start around late afternoon and continue into the night. It can cause increased confusion, disorientation, anxiety, agitation, pacing and even wandering.
Superset Stack Recovery Protocol (SSR): We stack our modalities believing that the coupling provides exponential results as each modality allows for better results for the corresponding modality. So, we create a super set of the treatments and stick them with other treatments.
Sympathetic Nervous System: A division of the nervous system that functions to produce localized adjustments (such as sweating as a response to an increase in temperature) and reflex adjustments of the cardiovascular system.
Synaptic connections: Synapses are part of the circuit that connects sensory organs, like those that detect pain or touch, in the peripheral nervous system to the brain. Synapses connect neurons in the brain to neurons in the rest of the body and from those neurons to the muscles.
Thermogenic: Relating to, caused by, or inducing the production of heat; also: producing heat.
Tinnitus: Ringing or buzzing noise in one or both ears that may be constant or come and go, often associated with hearing loss.
Transcranial Photobiomodulation: Light being delivered through the cranium at an amplitude of 1080 to modify or influence the cells of the patients CNS to create stimulation and influence to mirror the active levels of the frequency being delivered.
Traumatic Brain Injury (TBI): Brain dysfunction caused by an outside force, usually a violent blow to the head. Traumatic brain injury often occurs because of a severe sports injury or car accident. Yet new research is showing less invasive injuries can add up to mTBI symptoms, subconcussive or maybe should be referred to as PCS as they can become long term alterations in cognitive function. The long-term result of these head injuries included problems with memory, planning and perception, the review found. One study noted that professional soccer players who engaged in the most heading performed the worst on verbal and visual memory tests as well as tests of their attention span. It seems straightforward to assume the same with youth football as well as other youth sports such as the acrobatics of cheerleading. We see around five to eight girls a month have what are presumed to be concussions as hardly any have been tested.
Traumatic Brain Injury (TBI): Brain dysfunction caused by an outside force, usually a violent blow to the head. Traumatic brain injury often occurs because of a severe sports injury or car accident. Yet new research is showing less invasive injuries can add up to mTBI symptoms, subconcussive or maybe should be referred to as PCS as they can become long term alterations in cognitive function. The long-term result of these head injuries included problems with memory, planning and perception, the review found. One study noted that professional soccer players who engaged in the most heading performed the worst on verbal and visual memory tests as well as tests of their attention span. It seems straightforward to assume the same with youth football as well as other youth sports such as the acrobatics of cheerleading. We see around five to eight girls a month have what are presumed to be concussions as hardly any have been tested.
The Glasgow Coma Score (GCS) has traditionally been used to classify TBI as mild (GCS 13-15), moderate (GCS 9-12), or severe (GCS 3-8). The Glasgow Coma Scale is a clinical scale used to reliably measure a person's level of consciousness after a brain injury. The GCS assesses a person based on their ability to perform eye movements, speak, and move their body. These three behaviors make up the three elements of the scale: eye, verbal, and motor, skills
Most of those hits in youth football were modest in force, as measured by sensors installed in the padding of helmets. But some topped 80 g's, like "some of the more severe impacts that college players experience, even though the youth players have less body mass and play at slower speeds. We believe that around 10% of youth football players are capable of 65 to 80 g’s and this can cause subcucussive problems. Additionally, we believe the brain to be more vulnerable and possibly effect more sensitive areas such as the pituitary gland and its signals coming from the hippocampus.

Vagal Nerve: The vagus nerve, also known as the vagal nerves, are the main nerves of your parasympathetic nervous system. This system controls specific body functions such as your digestion, heart rate and immune system. These functions are involuntary, meaning you can't consciously control them.
Vagal: Latin meaning wandering, wambling, and strolling.
Vibragenixs: A form of whole-body vibration that uses sound frequencies to create the vibration. We believe by using specific sound frequencies such as 40 Hz and 10 Hz, in addition to 432 and other specific frequencies, it seems to penetrate more deeply in its ability to cause improved blood flow as well as frequencies known to have positive influences on the brain.
Vitamin A: A vitamin is an organic molecule that is an essential micronutrient which an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the diet.
Vitamin D: Vitamin D is a hormone rather than a vitamin; it is required to absorb calcium from the gut into the bloodstream. Vitamin D is mostly produced in the skin in response to sunlight and is also absorbed from food eaten (about 10% of vitamin D is absorbed this way) as part of a healthy balanced diet.
Whole Body Vibration: Mayo Clinic says Advocates of (WBV) say that as little as 15 minutes a day of whole-body vibration three times a week may aid weight loss, burn fat, improve flexibility, enhance blood flow, reduce muscle soreness after exercise, build strength and decrease the stress hormone cortisol. We mainly use to enhance blood flow
Parkinsonian syndromes include idiopathic Parkinson disease (PD), progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and vascular Parkinsonism (VaP), among other rarer causes of parkinsonism.

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